GLP-1s are being overused by people who don't even need them!
We are definitely going to see an increased risk of gallbladder/bile issues population wide if this trend continues.
A calorie deficit works for fat loss; you don't need GLPs in the vast majority of cases.
The funniest thing is that people have produced studies and use them to conclude, “Diet and exercise do not work.” and they use it to boost GLPs even more.
>Calorie deficit works, but the ability for an average person to maintain a calorie deficit without external help is close to 0%
I don't agree with 0% figure at all.
Why? because we are able to offer Guaranteed results AT NO COST (no ads, no subscription, no payment of any kind) within 2-3 weeks for both Weight Loss and Weight Gain, many people start seeing results from the very first week; you can read reviews if you doubt this.
The market is filled with "Eat X for weight loss, eat Y for weight gain."
The average person actually does not choose the right strategy for weight loss, which is a "calorie deficit."
But implementing it is not "EASY" until you understand how expenditure, calorie intake, and weight movement work, which is too much work to understand for an average Joe.
OKAY, the vast majority of people on Hacker News can probably wrap their heads around these concepts if they find the right resource, but the average Joe can't.
Let's take something as simple as "calorie deficit."
Being at a calorie deficit itself requires knowing two things:
1. How much you burn in a day (total daily energy expenditure or TDEE)
2. How much your intake is for the day
Deficit = TDEE - Intake
You can do calorie counting for #2. But what can you do for #1?
The average guy does not know how to calculate these properly, let alone judge weight movement, which can move a lot in the opposite direction due to water weight fluctuations that can exceed 1 kg+ of movement a day.
This is another misconception because of those "dieting studies" people believe dieting = VLCD or PSMF or other harsh deficit methods.
Running moderate deficit is key specially as a newbie.
Most people do not get fat because they are eating 1000s of calories in surplus each day; in fact, most people get fat over a long period of time and they might be eating only 100-200kcal more than what they need to maintain their weight or perhaps after getting fat they are eating at maintenance.
If you remove 300 kcal from your diet, you'll perhaps not even notice this, yet you'll end up losing 14 kg or 30 lbs in a year without much effort.
Very few people actually need GLPs for "appetite suppression."
If you want to run 1000 kcal deficits, GLPs make it very easy for people to crash their intake.
Crashing intake may result in bile/gallbladder issue or hairloss
GLP-1s are being overused by people who don't even need them! We are definitely going to see an increased risk of gallbladder/bile issues population wide if this trend continues.
A calorie deficit works for fat loss; you don't need GLPs in the vast majority of cases.
The funniest thing is that people have produced studies and use them to conclude, “Diet and exercise do not work.” and they use it to boost GLPs even more.
Calorie deficit works, but the ability for an average person to maintain a calorie deficit without external help is close to 0%
Just about every study ever done on diet and exercise shows this.
>Calorie deficit works, but the ability for an average person to maintain a calorie deficit without external help is close to 0%
I don't agree with 0% figure at all.
Why? because we are able to offer Guaranteed results AT NO COST (no ads, no subscription, no payment of any kind) within 2-3 weeks for both Weight Loss and Weight Gain, many people start seeing results from the very first week; you can read reviews if you doubt this.
The market is filled with "Eat X for weight loss, eat Y for weight gain."
The average person actually does not choose the right strategy for weight loss, which is a "calorie deficit."
But implementing it is not "EASY" until you understand how expenditure, calorie intake, and weight movement work, which is too much work to understand for an average Joe.
OKAY, the vast majority of people on Hacker News can probably wrap their heads around these concepts if they find the right resource, but the average Joe can't.
Let's take something as simple as "calorie deficit."
Being at a calorie deficit itself requires knowing two things:
1. How much you burn in a day (total daily energy expenditure or TDEE)
2. How much your intake is for the day
Deficit = TDEE - Intake
You can do calorie counting for #2. But what can you do for #1?
The average guy does not know how to calculate these properly, let alone judge weight movement, which can move a lot in the opposite direction due to water weight fluctuations that can exceed 1 kg+ of movement a day.
Have you seen the math required for figuring out "Maintenance Calories?, see this: https://macrocodex.app/knowledge/rethink/adaptive-tdee/
And all the factors that go into this? see this: https://macrocodex.app/knowledge/macrocodex/smart-calorie-bu...
We've 17,000+ users why? because #1 is a difficult problem for many.
Our solution is Macrocodex, which comes at no cost to the user and is very easy to use.
>Just about every study ever done on diet and exercise shows this.
Those studies already set people up for failure to begin with; I wrote about it here: https://macrocodex.app/knowledge/rethink/weight-loss-studies...
Yes, if only I could math, then the food cravings would stop..
This is another misconception because of those "dieting studies" people believe dieting = VLCD or PSMF or other harsh deficit methods.
Running moderate deficit is key specially as a newbie.
Most people do not get fat because they are eating 1000s of calories in surplus each day; in fact, most people get fat over a long period of time and they might be eating only 100-200kcal more than what they need to maintain their weight or perhaps after getting fat they are eating at maintenance.
If you remove 300 kcal from your diet, you'll perhaps not even notice this, yet you'll end up losing 14 kg or 30 lbs in a year without much effort.
Very few people actually need GLPs for "appetite suppression."
If you want to run 1000 kcal deficits, GLPs make it very easy for people to crash their intake.
Crashing intake may result in bile/gallbladder issue or hairloss
Even GLP users recommend the macrocodex:
https://www.reddit.com/r/tirzepatidecompound/comments/1omfgx...
why blame the users when it’s the makers of the poor food that should be blamed
The market has a lot of food choices.
You can still get fat eating organic whole foods; butter tastes good, and it's easy to overeat.
The issue is people not having a good enough activity level and then getting fat, and swinging to the opposite extreme by crash dieting.
GLPs make it very easy to crash diet which results in other issues.
Once a person understands how calories map to weight changes over a period of time, it becomes very easy for them!
“Potential residual confounding and selection bias restrict generalisability of the results.”
Will be interesting to see more RCTs for these drugs over the next decade to see how far their benefits stretch.
Study: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0...